CAPON GROUP - We specialize in the detection, isolation, identification and evaluation of biologically active small molecules from Nature (natural products). Our goal is to acquire knowledge of the chemical and biological properties of natural products, including how and why they are made, and to use this knowledge to better understand living systems, and inspire innovative solutions for important scientific and societal challenges.
In recent years the Capon Group has studied several thousand natural products, many rare or new to science, and with valuable chemical and biological properties. We have made numerous discoveries across basic and applied science, providing valuable undergraduate, postgraduate and professional training, and generating multiple high impact publications, and several patents. As internationally recognised experts in organic and natural products chemistry, as well as analytical and medicinal chemistry, and chemical ecology, we have established specialist capabilities across;
Microbiology – The isolation and cultivation of bacterial and fungal strains.
Chemistry – The isolation, structure elucidation and synthesis of natural products and related analogues.
Biology – The evaluation of extracts and natural products against an array of bioassays.
Capon Group research activities are currently organized around five thematic programs;
Marine Biodiscovery: Documenting, evaluating and exploiting the chemical and biological properties of natural products from Australian marine invertebrates and algae.
Microbial Biodiscovery: Documenting, evaluating and exploiting the chemical and biological properties of natural products from Australian marine and terrestrial, bacteria and fungi.
Chemical Ecology: Documenting, evaluating and exploiting chemical communication between members of the same or different species – extending across microbes, plants, insects and animals.
Pharmaceutical Biodiscovery: Applying knowledge of natural products to inspire the development of new pharmaceuticals, with a particular focus on neurodegenerative and infectious diseases, cancer and pain.
Agrochemical Biodiscovery: Applying knowledge of natural products to inspire the development of agrochemicals, to enhance the health and productivity of livestock and crops.
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